The Role of Pyroptosis and Autophagy in Ischemia Reperfusion Injury

Pyroptosis is a process of programmed cell death mediated by gasdermin (GSDM) found in recent years. In the process of pyroptosis, caspase-1 or caspase-11/4/5 is activated, which cleaves gasdermin D and separates its N-terminal pore-forming domain (PFD). The oligomers of PFD bind to the cell membran...

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Detalles Bibliográficos
Autores principales: Zhao, Huijie, Yang, Yihan, Si, Xinya, Liu, Huiyang, Wang, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313059/
https://www.ncbi.nlm.nih.gov/pubmed/35883566
http://dx.doi.org/10.3390/biom12071010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313059/
https://www.ncbi.nlm.nih.gov/pubmed/35883566
http://dx.doi.org/10.3390/biom12071010

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