α-Synuclein Conformational Plasticity: Physiologic States, Pathologic Strains, and Biotechnological Applications

α-Synuclein (αS) is remarkable for both its extensive conformational plasticity and pathologic prion-like properties. Physiologically, αS may populate disordered monomeric, helically folded tetrameric, or membrane-bound oligomeric states. Pathologically, αS may assemble into toxic oligomers and subs...

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Detalles Bibliográficos
Autores principales: Li, Amanda, Rastegar, Cyrus, Mao, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313095/
https://www.ncbi.nlm.nih.gov/pubmed/35883550
http://dx.doi.org/10.3390/biom12070994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313095/
https://www.ncbi.nlm.nih.gov/pubmed/35883550
http://dx.doi.org/10.3390/biom12070994

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