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Metformin Is Associated with the Inhibition of Renal Artery AT1R/ET-1/iNOS Axis in a Rat Model of Diabetic Nephropathy with Suppression of Inflammation and Oxidative Stress and Kidney Injury

Diabetes is the most common cause of end-stage renal disease, also called kidney failure. The link between the renal artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET-1), involved in vasoconstriction, oxidative stress, inflammation and kidney fibrosis (collagen) in diabetes-induced n...

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Detalles Bibliográficos
Autores principales: Dawood, Amal F., Maarouf, Amro, Alzamil, Norah M., Momenah, Maha A., Shati, Ayed A., Bayoumy, Nervana M., Kamar, Samaa S., Haidara, Mohamed A., ShamsEldeen, Asmaa M., Yassin, Hanaa Z., Hewett, Peter W., Al-Ani, Bahjat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313150/
https://www.ncbi.nlm.nih.gov/pubmed/35884947
http://dx.doi.org/10.3390/biomedicines10071644