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Metformin Is Associated with the Inhibition of Renal Artery AT1R/ET-1/iNOS Axis in a Rat Model of Diabetic Nephropathy with Suppression of Inflammation and Oxidative Stress and Kidney Injury
Diabetes is the most common cause of end-stage renal disease, also called kidney failure. The link between the renal artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET-1), involved in vasoconstriction, oxidative stress, inflammation and kidney fibrosis (collagen) in diabetes-induced n...
Autores principales: | Dawood, Amal F., Maarouf, Amro, Alzamil, Norah M., Momenah, Maha A., Shati, Ayed A., Bayoumy, Nervana M., Kamar, Samaa S., Haidara, Mohamed A., ShamsEldeen, Asmaa M., Yassin, Hanaa Z., Hewett, Peter W., Al-Ani, Bahjat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313150/ https://www.ncbi.nlm.nih.gov/pubmed/35884947 http://dx.doi.org/10.3390/biomedicines10071644 |
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