Computational Analysis of Pathogenetic Pathways in Alzheimer’s Disease and Prediction of Potential Therapeutic Drugs

Background. Alzheimer’s disease (AD) is a chronic and progressive neurodegenerative disease which affects more than 50 million patients and represents 60–80% of all cases of dementia. Mutations in the APP gene, mostly affecting the γ-secretase site of cleavage and presenilin mutations, have been ide...

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Detalles Bibliográficos
Autores principales: Petralia, Maria Cristina, Mangano, Katia, Quattropani, Maria Catena, Lenzo, Vittorio, Nicoletti, Ferdinando, Fagone, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313152/
https://www.ncbi.nlm.nih.gov/pubmed/35884634
http://dx.doi.org/10.3390/brainsci12070827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313152/
https://www.ncbi.nlm.nih.gov/pubmed/35884634
http://dx.doi.org/10.3390/brainsci12070827

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