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The Role of Tryptophan Dysmetabolism and Quinolinic Acid in Depressive and Neurodegenerative Diseases

Emerging evidence suggests that neuroinflammation is involved in both depression and neurodegenerative diseases. The kynurenine pathway, generating metabolites which may play a role in pathogenesis, is one of several competing pathways of tryptophan metabolism. The present article is a narrative rev...

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Detalles Bibliográficos
Autores principales: Hestad, Knut, Alexander, Jan, Rootwelt, Helge, Aaseth, Jan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313172/
https://www.ncbi.nlm.nih.gov/pubmed/35883554
http://dx.doi.org/10.3390/biom12070998