In-Silico Analysis of pH-Dependent Liquid-Liquid Phase Separation in Intrinsically Disordered Proteins

Intrinsically disordered proteins (IDPs) are essential players in the assembly of biomolecular condensates during liquid–liquid phase separation (LLPS). Disordered regions (IDRs) are significantly exposed to the solvent and, therefore, highly influenced by fluctuations in the microenvironment. Extri...

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Detalles Bibliográficos
Autores principales: Pintado-Grima, Carlos, Bárcenas, Oriol, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313257/
https://www.ncbi.nlm.nih.gov/pubmed/35883530
http://dx.doi.org/10.3390/biom12070974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313257/
https://www.ncbi.nlm.nih.gov/pubmed/35883530
http://dx.doi.org/10.3390/biom12070974

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