An Oral 3D Printed PLGA-Tocopherol PEG Succinate Nanocomposite Hydrogel for High-Dose Methotrexate Delivery in Maintenance Chemotherapy

High-dose methotrexate (HDMTX) is one of the chemotherapeutic agents used to treat a variety of cancers in both adults and children. However, the toxicity associated with HDMTX has resulted in the spread of infections and treatment interruption. Further, poor bioavailability due to efflux pump activ...

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Detalles Bibliográficos
Autores principales: Kondiah, Pierre P. D., Rants’o, Thankhoe A., Makhathini, Sifiso S., Mdanda, Sipho, Choonara, Yahya E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313284/
https://www.ncbi.nlm.nih.gov/pubmed/35884775
http://dx.doi.org/10.3390/biomedicines10071470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313284/
https://www.ncbi.nlm.nih.gov/pubmed/35884775
http://dx.doi.org/10.3390/biomedicines10071470

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