Cargando…

An Oral 3D Printed PLGA-Tocopherol PEG Succinate Nanocomposite Hydrogel for High-Dose Methotrexate Delivery in Maintenance Chemotherapy

High-dose methotrexate (HDMTX) is one of the chemotherapeutic agents used to treat a variety of cancers in both adults and children. However, the toxicity associated with HDMTX has resulted in the spread of infections and treatment interruption. Further, poor bioavailability due to efflux pump activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kondiah, Pierre P. D., Rants’o, Thankhoe A., Makhathini, Sifiso S., Mdanda, Sipho, Choonara, Yahya E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313284/ https://www.ncbi.nlm.nih.gov/pubmed/35884775 http://dx.doi.org/10.3390/biomedicines10071470

Ejemplares similares

A Poly (Caprolactone)-Cellulose Nanocomposite Hydrogel for Transdermal Delivery of Hydrocortisone in Treating Psoriasis Vulgaris
por: Kondiah, Pierre P. D., et al.
Publicado: (2022)

Biomedicine Innovations and Its Nanohydrogel Classifications
por: Makhathini, Sifiso S., et al.
Publicado: (2022)

A Micro-In-Macro Gastroretentive System for the Delivery of Narrow-Absorption Window Drugs
por: Govender, Mershen, et al.
Publicado: (2023)

Comparative Nanofabrication of PLGA-Chitosan-PEG Systems Employing Microfluidics and Emulsification Solvent Evaporation Techniques
por: Essa, Divesha, et al.
Publicado: (2020)

Recent Advances in Microneedle Platforms for Transdermal Drug Delivery Technologies
por: Mdanda, Sipho, et al.
Publicado: (2021)

Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review
por: Rants’o, Thankhoe A., et al.
Publicado: (2022)

Thermo-Responsive Nanocomposite Hydrogels Based on PEG-b-PLGA Diblock Copolymer and Laponite
por: Maeda, Tomoki, et al.
Publicado: (2019)

Thermosensitive PLGA–PEG–PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy
por: Heine, Sonja, et al.
Publicado: (2022)

Advanced Hydrogels for the Controlled Delivery of Insulin
por: Mansoor, Shazia, et al.
Publicado: (2021)

Design of Chitosan-Coated, Quercetin-Loaded PLGA Nanoparticles for Enhanced PSMA-Specific Activity on LnCap Prostate Cancer Cells
por: Essa, Divesha, et al.
Publicado: (2023)

Neuroprotective effect of insulin-loaded chitosan nanoparticles/PLGA-PEG-PLGA hydrogel on diabetic retinopathy in rats
por: Rong, Xianfang, et al.
Publicado: (2018)

Investigating a Curcumin-Loaded PLGA-PEG-PLGA Thermo-Sensitive Hydrogel for the Prevention of Alzheimer’s Disease
por: Lin, Yi-Wen, et al.
Publicado: (2022)

Development of PLGA-PEG-PLGA Hydrogel Delivery System for Enhanced Immunoreaction and Efficacy of Newcastle Disease Virus DNA Vaccine
por: Gao, Ying, et al.
Publicado: (2020)

Doxorubicin and CD-CUR inclusion complex co-loaded in thermosensitive hydrogel PLGA-PEG-PLGA localized administration for osteosarcoma
por: Yang, Zhiming, et al.
Publicado: (2020)

Intracranial In Situ Thermosensitive Hydrogel Delivery of Temozolomide Accomplished by PLGA–PEG–PLGA Triblock Copolymer Blending for GBM Treatment
por: Gu, Weinan, et al.
Publicado: (2022)

The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition
por: Rants’o, Thankhoe A., et al.
Publicado: (2022)

A Review of Injectable Polymeric Hydrogel Systems for Application in Bone Tissue Engineering
por: Kondiah, Pariksha J., et al.
Publicado: (2016)

Thermo-Responsive PLGA-PEG-PLGA Hydrogels as Novel Injectable Platforms for Neuroprotective Combined Therapies in the Treatment of Retinal Degenerative Diseases
por: López-Cano, José Javier, et al.
Publicado: (2021)

PLGA-PEG-PLGA hydrogel with NEP1-40 promotes the functional recovery of brachial plexus root avulsion in adult rats
por: Guo, Wenlai, et al.
Publicado: (2021)

Assessment of the Effect of PLGA Co-polymers and PEG on the Formation and Characteristics of PLGA-PEG-PLGA Co-block Polymer Using Statistical Approach
por: Sulaiman, Teuku Nanda Saifullah, et al.
Publicado: (2019)

DPD simulations on morphologies and structures of blank PLGA-b-PEG-b-PLGA polymeric micelles and docetaxel-loaded PLGA-b-PEG-b-PLGA polymeric micelles
por: Wang, Mengyao, et al.
Publicado: (2022)

PEG–PLGA nanoparticles for encapsulating ciprofloxacin
por: Watcharadulyarat, Natsorn, et al.
Publicado: (2023)

Radioprotective properties of tocopherol succinate against ionizing radiation in mice
por: Singh, Vijay K., et al.
Publicado: (2013)

Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers
por: Movaffagh, Jebraeil, et al.
Publicado: (2022)

Hydrogel Biomaterials for Application in Ocular Drug Delivery
por: Lynch, Courtney R., et al.
Publicado: (2020)

A Closed Loop Stimuli-Responsive Concanavalin A-Loaded Chitosan–Pluronic Hydrogel for Glucose-Responsive Delivery of Short-Acting Insulin Prototyped in RIN-5F Pancreatic Cells
por: Mansoor, Shazia, et al.
Publicado: (2023)

Molecule(s) of Interest: I. Ionic Liquids–Gateway to Newer Nanotechnology Applications: Advanced Nanobiotechnical Uses’, Current Status, Emerging Trends, Challenges, and Prospects
por: Khan, Riaz A., et al.
Publicado: (2022)

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile
por: Rafiei, Pedram, et al.
Publicado: (2017)

Dual Drug Delivery of Sorafenib and Doxorubicin from PLGA and PEG-PLGA Polymeric Nanoparticles
por: Babos, György, et al.
Publicado: (2018)

Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles
por: Fodor-Kardos, Andrea, et al.
Publicado: (2020)

Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model
por: Al-Thani, Hissa F., et al.
Publicado: (2022)

Development of α-Tocopherol Succinate-Based Nanostructured Lipid Carriers for Delivery of Paclitaxel
por: Marathe, Sushrut, et al.
Publicado: (2022)

Drug-loaded PEG-PLGA nanoparticles for cancer treatment
por: Zhang, Dan, et al.
Publicado: (2022)

Injectable In-Situ Forming Depot Based on PLGA and PLGA-PEG-PLGA for Sustained-Release of Risperidone: In Vitro Evaluation and Pharmacokinetics in Rabbits
por: Rezaeian Shiadeh, Seyedeh Nesa, et al.
Publicado: (2023)

Synthesis and computational investigation of molecularly imprinted nanospheres for selective recognition of alpha-tocopherol succinate
por: Piacham, Theeraphon, et al.
Publicado: (2013)

Nanoemulsion Composed of α-Tocopherol Succinate and Dequalinium Shows Mitochondria-Targeting and Anticancer Effects
por: Thuy, Le Thi, et al.
Publicado: (2023)

Design of a Versatile pH-Responsive Hydrogel for Potential Oral Delivery of Gastric-Sensitive Bioactives
por: Hibbins, Angus R., et al.
Publicado: (2017)

Process analytical technology as in-process control tool in semi-continuous manufacturing of PLGA/PEG-PLGA microspheres
por: Anwar, Arfidin, et al.
Publicado: (2023)

Endostar-loaded PEG-PLGA nanoparticles: in vitro and in vivo evaluation
por: Hu, Sanyuan, et al.
Publicado: (2010)

Shape dependent cytotoxicity of PLGA-PEG nanoparticles on human cells
por: Zhang, Bokai, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gng2pjaaavd6ji3ivt3cqjkse3