Novel Endometrial Cancer Models Using Sensitive Metastasis Tracing for CXCR4-Targeted Therapy in Advanced Disease

Advanced endometrial cancer (EC) lacks therapy, thus, there is a need for novel treatment targets. CXCR4 overexpression is associated with a poor prognosis in several cancers, whereas its inhibition prevents metastases. We assessed CXCR4 expression in EC in women by using IHC. Orthotopic models were...

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Detalles Bibliográficos
Autores principales: Medina-Gutiérrez, Esperanza, Céspedes, María Virtudes, Gallardo, Alberto, Rioja-Blanco, Elisa, Pavón, Miquel Àngel, Asensio-Puig, Laura, Farré, Lourdes, Alba-Castellón, Lorena, Unzueta, Ugutz, Villaverde, Antonio, Vázquez, Esther, Casanova, Isolda, Mangues, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313294/
https://www.ncbi.nlm.nih.gov/pubmed/35884987
http://dx.doi.org/10.3390/biomedicines10071680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313294/
https://www.ncbi.nlm.nih.gov/pubmed/35884987
http://dx.doi.org/10.3390/biomedicines10071680

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