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Cardiac Cx43 Signaling Is Enhanced and TGF-β1/SMAD2/3 Suppressed in Response to Cold Acclimation and Modulated by Thyroid Status in Hairless SHR(M)

The hearts of spontaneously hypertensive rats (SHR) are prone to malignant arrhythmias, mainly due to disorders of electrical coupling protein Cx43 and the extracellular matrix. Cold acclimation may induce cardio-protection, but the underlying mechanisms remain to be elucidated. We aimed to explore...

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Detalles Bibliográficos
Autores principales: Andelova, Katarina, Szeiffova Bacova, Barbara, Sykora, Matus, Pavelka, Stanislav, Rauchova, Hana, Tribulova, Narcis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313296/
https://www.ncbi.nlm.nih.gov/pubmed/35885012
http://dx.doi.org/10.3390/biomedicines10071707