Expression of a PCSK9 Gain-of-Function Mutation in C57BL/6J Mice to Facilitate Angiotensin II-Induced AAAs

Angiotensin II (AngII) infusion in mice has been used widely to investigate mechanisms of abdominal aortic aneurysms (AAAs). To achieve a high incidence of AngII-induced AAAs, mice should be hypercholesterolemic. Therefore, either low-density lipoprotein receptor (LDLR) or apolipoprotein E deficienc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sawada, Hisashi, Daugherty, Alan, Lu, Hong S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313338/
https://www.ncbi.nlm.nih.gov/pubmed/35883473
http://dx.doi.org/10.3390/biom12070915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313338/
https://www.ncbi.nlm.nih.gov/pubmed/35883473
http://dx.doi.org/10.3390/biom12070915

Ejemplares similares