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Nephroprotective Effects of Semaglutide as Mono- and Combination Treatment with Lisinopril in a Mouse Model of Hypertension-Accelerated Diabetic Kidney Disease

Background: Obesity, hyperglycemia and hypertension are critical risk factors for development of diabetic kidney disease (DKD). Emerging evidence suggests that glucagon-like peptide-1 receptor (GLP-1R) agonists improve cardiovascular and renal outcomes in type 2 diabetes patients. Here, we character...

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Detalles Bibliográficos
Autores principales: Dalbøge, Louise S., Christensen, Michael, Madsen, Martin Rønn, Secher, Thomas, Endlich, Nicole, Drenic’, Vedran, Manresa-Arraut, Alba, Hansen, Henrik H., Rune, Ida, Fink, Lisbeth N., Østergaard, Mette V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313388/
https://www.ncbi.nlm.nih.gov/pubmed/35884965
http://dx.doi.org/10.3390/biomedicines10071661