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Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design
In the context of the structural complexity necessary for a molecule to selectively display a therapeutical action and the requirements for suitable pharmacokinetics, a robust synthetic approach is essential. Typically, thousands of relatively similar compounds should be prepared along the drug disc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313418/ https://www.ncbi.nlm.nih.gov/pubmed/35884794 http://dx.doi.org/10.3390/biomedicines10071488 |