Cargando…
Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design
In the context of the structural complexity necessary for a molecule to selectively display a therapeutical action and the requirements for suitable pharmacokinetics, a robust synthetic approach is essential. Typically, thousands of relatively similar compounds should be prepared along the drug disc...
Autores principales: | Nadal Rodríguez, Pau, Ghashghaei, Ouldouz, Bagán, Andrea, Escolano, Carmen, Lavilla, Rodolfo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313418/ https://www.ncbi.nlm.nih.gov/pubmed/35884794 http://dx.doi.org/10.3390/biomedicines10071488 |
Ejemplares similares
-
Selectivity in multiple multicomponent reactions: types and synthetic applications
por: Ghashghaei, Ouldouz, et al.
Publicado: (2019) -
Multicomponent Reactions Upon the Known Drug Trimethoprim as a Source of Novel Antimicrobial Agents
por: Pedrola, Marina, et al.
Publicado: (2019) -
Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions
por: Trejo, Angela, et al.
Publicado: (2023) -
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations
por: Ghashghaei, Ouldouz, et al.
Publicado: (2014) -
Isocyanide-Based Multicomponent Reactions for the Synthesis of Heterocycles
por: Váradi, András, et al.
Publicado: (2015)