CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4‐Fatty Acid β‐Oxidation Pathway

Metabolic reprogramming is often observed in carcinogenesis, but little is known about the aberrant metabolic genes involved in the tumorigenicity and maintenance of stemness in cancer cells. Sixty‐seven oncogenic metabolism‐related genes in liver cancer by in vivo CRISPR/Cas9 screening are identifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hongquan, Song, Junjiao, He, Yifei, Liu, Yizhe, Liu, Zhen, Sun, Weili, Hu, Weiguo, Lei, Qun‐Ying, Hu, Xin, Chen, Zhiao, He, Xianghuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313492/
https://www.ncbi.nlm.nih.gov/pubmed/35603967
http://dx.doi.org/10.1002/advs.202105126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313492/
https://www.ncbi.nlm.nih.gov/pubmed/35603967
http://dx.doi.org/10.1002/advs.202105126

Ejemplares similares