A Small Molecule Selected from a DNA‐Encoded Library of Natural Products That Binds to TNF‐α and Attenuates Inflammation In Vivo

Tumor necrosis factor α (TNF‐α) inhibitors have shown great success in the treatment of autoimmune diseases. However, to date, approved drugs targeting TNF‐α are restricted to biological macromolecules, largely due to the difficulties in using small molecules for pharmaceutical intervention of prote...

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Detalles Bibliográficos
Autores principales: Wang, Shuyue, Shi, Xiaojie, Li, Jie, Huang, Qianping, Ji, Qun, Yao, Ying, Wang, Tao, Liu, Lili, Ye, Min, Deng, Yun, Ma, Peixiang, Xu, Hongtao, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313502/
https://www.ncbi.nlm.nih.gov/pubmed/35596609
http://dx.doi.org/10.1002/advs.202201258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313502/
https://www.ncbi.nlm.nih.gov/pubmed/35596609
http://dx.doi.org/10.1002/advs.202201258

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