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Process- and product-related impurities in the ChAdOx1 nCov-19 vaccine

ChAdOx1 nCov-19 and Ad26.COV2.S are approved vaccines inducing protective immunity against SARS-CoV-2 infection in humans by expressing the Spike protein of SARS-CoV-2. We analyzed protein content and protein composition of ChAdOx1 nCov-19 and Ad26.COV2.S by biochemical methods and by mass spectrome...

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Detalles Bibliográficos
Autores principales: Krutzke, Lea, Rösler, Reinhild, Allmendinger, Ellen, Engler, Tatjana, Wiese, Sebastian, Kochanek, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313527/
https://www.ncbi.nlm.nih.gov/pubmed/35781137
http://dx.doi.org/10.7554/eLife.78513