Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss in mice promotes chronic liver damage and leads to HCC. Hepatocyte‐specific SRSF3 knockout mice (SKO mice) also overexpre...

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Detalles Bibliográficos
Autores principales: Kumar, Deepak, Das, Manasi, Oberg, Alexis, Sahoo, Debashis, Wu, Panyisha, Sauceda, Consuelo, Jih, Lily, Ellies, Lesley G., Langiewicz, Magda T., Sen, Supriya, Webster, Nicholas J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313545/
https://www.ncbi.nlm.nih.gov/pubmed/35615981
http://dx.doi.org/10.1002/advs.202105120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313545/
https://www.ncbi.nlm.nih.gov/pubmed/35615981
http://dx.doi.org/10.1002/advs.202105120

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