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Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss in mice promotes chronic liver damage and leads to HCC. Hepatocyte‐specific SRSF3 knockout mice (SKO mice) also overexpre...
Autores principales: | Kumar, Deepak, Das, Manasi, Oberg, Alexis, Sahoo, Debashis, Wu, Panyisha, Sauceda, Consuelo, Jih, Lily, Ellies, Lesley G., Langiewicz, Magda T., Sen, Supriya, Webster, Nicholas J. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313545/ https://www.ncbi.nlm.nih.gov/pubmed/35615981 http://dx.doi.org/10.1002/advs.202105120 |
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