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Influence of conventional hydrogen bonds in the intercalation of phenanthroline derivatives with DNA: The important role of the sugar and phosphate backbone

The influence of hydrogen bonds in model intercalated systems between guanine‐cytosine and adenine‐thymine DNA base pairs (bps) was analyzed with the popular intercalator 1,10‐phenanthroline (phen) and derivatives obtained by substitution with —OH and —NH(2) groups in positions 4 and 7. Semiempirica...

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Detalles Bibliográficos
Autores principales: Sánchez‐González, Ángel, Grenut, Pierre, Gil, Adrià
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313584/
https://www.ncbi.nlm.nih.gov/pubmed/35297513
http://dx.doi.org/10.1002/jcc.26836