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Stereo‐Divergent Enzyme Cascades to Convert Racemic 4‐Phenyl‐2‐Butanol into either (S)‐ or (R)‐Corresponding Chiral Amine

The synthesis of enantiopure chiral amines from racemic alcohols is a key transformation in the chemical industry, e. g., in the production of active pharmaceutical ingredients (APIs). However, this reaction remains challenging. In this work, we propose a one‐pot enzymatic cascade for the direct con...

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Detalles Bibliográficos
Autores principales: Romero‐Fernandez, Maria, Paradisi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313814/
https://www.ncbi.nlm.nih.gov/pubmed/35189014
http://dx.doi.org/10.1002/cbic.202200108