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Synthesis of [(2)H(5)]baricitinib via [(2)H(5)]ethanesulfonyl chloride

Baricitinib, typically applied as a treatment for rheumatoid arthritis, has recently attracted the attention of clinicians and researchers as a potential treatment for COVID‐19. Naturally, there has been a need for the preparation of the isotope‐labelled analogue of baricitinib to probe the pharmaco...

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Detalles Bibliográficos
Autores principales: Jansen‐van Vuuren, Ross D., Vohra, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313827/
https://www.ncbi.nlm.nih.gov/pubmed/35277889
http://dx.doi.org/10.1002/jlcr.3969