Effect of polypharmacy on bleeding with rivaroxaban versus vitamin K antagonist for treatment of venous thromboembolism

BACKGROUND: Polypharmacy, including use of inhibitors of CYP3A4 and P‐glycoprotein (P‐gp), is common in patients with venous thromboembolism (VTE) and is associated with increased bleeding. METHODS: In 8246 patients included in the EINSTEIN‐VTE studies for acute VTE, we evaluated the effect of polyp...

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Detalles Bibliográficos
Autores principales: Bistervels, Ingrid M., Bavalia, Roisin, Gebel, Martin, Lensing, Anthonie W. A., Middeldorp, Saskia, Prins, Martin H., Coppens, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
HAEMOSTASIS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313834/
https://www.ncbi.nlm.nih.gov/pubmed/35253983
http://dx.doi.org/10.1111/jth.15692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313834/
https://www.ncbi.nlm.nih.gov/pubmed/35253983
http://dx.doi.org/10.1111/jth.15692

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