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Efficacy of Tocilizumab Monotherapy Versus Tocilizumab and Methotrexate Combination Therapy in the Prevention of Radiographic Progression in Rheumatoid Arthritis: An Analysis Using Individual Patient Data From Multiple Clinical Trials

OBJECTIVE: To compare the effects of preventing radiographic progression (in its 3 components) of tocilizumab (TCZ) monotherapy with those of TCZ and methotrexate (MTX) in combination therapy (TCZ + MTX), and to evaluate possible effect modifiers in this model. METHODS: Randomized trials that compar...

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Detalles Bibliográficos
Autores principales: Verhoeven, Maxime M. A., Tekstra, Janneke, Jacobs, Johannes W. G., Bijlsma, Johannes W. J., van Laar, Jacob M., Pethö‐Schramm, Attila, Borm, Michelle E. A., Lafeber, Floris P. J., Welsing, Paco M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313860/
https://www.ncbi.nlm.nih.gov/pubmed/33253497
http://dx.doi.org/10.1002/acr.24524