Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa

BACKGROUND: Activated coagulation factor XI (FXIa) contributes to the development and propagation of thrombosis but plays only a minor role in hemostasis; therefore, it is an attractive antithrombotic target. OBJECTIVES: To evaluate the pharmacology of asundexian (BAY 2433334), a small molecule inhi...

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Detalles Bibliográficos
Autores principales: Heitmeier, Stefan, Visser, Mayken, Tersteegen, Adrian, Dietze‐Torres, Julia, Glunz, Julia, Gerdes, Christoph, Laux, Volker, Stampfuss, Jan, Roehrig, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
THROMBOSIS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313898/
https://www.ncbi.nlm.nih.gov/pubmed/35289054
http://dx.doi.org/10.1111/jth.15700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313898/
https://www.ncbi.nlm.nih.gov/pubmed/35289054
http://dx.doi.org/10.1111/jth.15700

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