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In vivo electrophysiological study of the targeting of 5‐HT(3) receptor‐expressing cortical interneurons by the multimodal antidepressant, vortioxetine

The antidepressant vortioxetine has high affinity for the ionotropic 5‐HT(3) receptor (5‐HT(3)R) as well as other targets including the 5‐HT transporter. The procognitive effects of vortioxetine have been linked to altered excitatory:inhibitory balance in cortex. Thus, vortioxetine purportedly inhib...

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Detalles Bibliográficos
Autores principales: Schweimer, Judith V., Brouard, Julia T., Li, Yan, Sánchez, Connie, Sharp, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314076/
https://www.ncbi.nlm.nih.gov/pubmed/35146812
http://dx.doi.org/10.1111/ejn.15623