Stiripentol inhibits spike‐and‐wave discharges in animal models of absence seizures: A new mechanism of action involving T‐type calcium channels

OBJECTIVE: Stiripentol (STP; Diacomit®) is an antiepileptic drug indicated for Dravet syndrome that has been identified as a γ‐aminobutyric acid (GABAergic) positive allosteric modulator. Dravet syndrome is characterized by multiple seizure types: generalized tonic–clonic, focal, myoclonic, and abse...

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Detalles Bibliográficos
Autores principales: Riban, Veronique, Heulard, Isabelle, Reversat, Lucie, Si Hocine, Hakim, Verleye, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314114/
https://www.ncbi.nlm.nih.gov/pubmed/35184274
http://dx.doi.org/10.1111/epi.17201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314114/
https://www.ncbi.nlm.nih.gov/pubmed/35184274
http://dx.doi.org/10.1111/epi.17201

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