Epigenetic Anti‐Cancer Treatment With a Stabilized Carbocyclic Decitabine Analogue

5‐Aza‐2’‐deoxycytidine (Decitabine, AzadC) is a nucleoside analogue, which is in clinical use to treat patients with myelodysplastic syndrome or acute myeloid leukemia. Its mode of action is unusual because the compound is one of the few drugs that act at the epigenetic level of the genetic code. Az...

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Detalles Bibliográficos
Autores principales: Traube, Franziska R., Brás, Natércia F., Roos, Wynand P., Sommermann, Corinna C., Diehl, Tamara, Mayer, Robert J., Ofial, Armin R., Müller, Markus, Zipse, Hendrik, Carell, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314125/
https://www.ncbi.nlm.nih.gov/pubmed/35285586
http://dx.doi.org/10.1002/chem.202200640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314125/
https://www.ncbi.nlm.nih.gov/pubmed/35285586
http://dx.doi.org/10.1002/chem.202200640

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