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Selective quantification of the 22-kDa isoform of human growth hormone 1 in serum and plasma by immunocapture and LC–MS/MS

The human growth hormone GH1 (22 kDa) is a commonly measured biomarker for diagnosis and during treatment of growth disorders, but its quantification by ligand binding assays may be compromised by the occurrence of a number of isoforms. These can interfere in the assays and lead to differences in re...

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Detalles Bibliográficos
Autores principales: Sleumer, Bas, van Faassen, Martijn, Vos, Michel J., Bischoff, Rainer, Kema, Ido P., van de Merbel, Nico C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314277/
https://www.ncbi.nlm.nih.gov/pubmed/35838770
http://dx.doi.org/10.1007/s00216-022-04188-z