Quality Assurance of PBPK Modeling Platforms and Guidance on Building, Evaluating, Verifying and Applying PBPK Models Prudently under the Umbrella of Qualification: Why, When, What, How and By Whom?

Modeling and simulation emerges as a fundamental asset of drug development. Mechanistic modeling builds upon its strength to integrate various data to represent a detailed structural knowledge of a physiological and biological system and is capable of informing numerous drug development and regulato...

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Detalles Bibliográficos
Autores principales: Frechen, Sebastian, Rostami-Hodjegan, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
White Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314283/
https://www.ncbi.nlm.nih.gov/pubmed/35445350
http://dx.doi.org/10.1007/s11095-022-03250-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314283/
https://www.ncbi.nlm.nih.gov/pubmed/35445350
http://dx.doi.org/10.1007/s11095-022-03250-w

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