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Microneedle-Mediated Permeation Enhancement of Chlorhexidine Digluconate: Mechanistic Insights Through Imaging Mass Spectrometry

PURPOSE: Chlorhexidine digluconate (CHG) is a first-line antiseptic agent typically applied to the skin as a topical solution prior to surgery due to its efficacy and safety profile. However, the physiochemical properties of CHG limits its cutaneous permeation, preventing it from reaching potentiall...

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Detalles Bibliográficos
Autores principales: Kirkby, Melissa, Sabri, Akmal Bin, Scurr, David, Moss, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314308/
https://www.ncbi.nlm.nih.gov/pubmed/35689005
http://dx.doi.org/10.1007/s11095-022-03309-8