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BMP3 inhibits TGFβ2-mediated myofibroblast differentiation during wound healing of the embryonic cornea

Often acute damage to the cornea initiates drastic tissue remodeling, resulting in fibrotic scarring that disrupts light transmission and precedes vision impairment. Very little is known about the factors that can mitigate fibrosis and promote scar-free cornea wound healing. We previously described...

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Detalles Bibliográficos
Autores principales: Spurlin, James W., Garis, Matthew R., Lwigale, Peter Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314337/
https://www.ncbi.nlm.nih.gov/pubmed/35879352
http://dx.doi.org/10.1038/s41536-022-00232-9