Cargando…

Postmitotic differentiation of human monocytes requires cohesin-structured chromatin

Cohesin is a major structural component of mammalian genomes and is required to maintain loop structures. While acute depletion in short-term culture models suggests a limited importance of cohesin for steady-state transcriptional circuits, long-term studies are hampered by essential functions of co...

Descripción completa

Detalles Bibliográficos
Autores principales: Minderjahn, Julia, Fischer, Alexander, Maier, Konstantin, Mendes, Karina, Nuetzel, Margit, Raithel, Johanna, Stanewsky, Hanna, Ackermann, Ute, Månsson, Robert, Gebhard, Claudia, Rehli, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314343/
https://www.ncbi.nlm.nih.gov/pubmed/35879286
http://dx.doi.org/10.1038/s41467-022-31892-2