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Postmitotic differentiation of human monocytes requires cohesin-structured chromatin
Cohesin is a major structural component of mammalian genomes and is required to maintain loop structures. While acute depletion in short-term culture models suggests a limited importance of cohesin for steady-state transcriptional circuits, long-term studies are hampered by essential functions of co...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314343/ https://www.ncbi.nlm.nih.gov/pubmed/35879286 http://dx.doi.org/10.1038/s41467-022-31892-2 |