Cargando…
Postmitotic differentiation of human monocytes requires cohesin-structured chromatin
Cohesin is a major structural component of mammalian genomes and is required to maintain loop structures. While acute depletion in short-term culture models suggests a limited importance of cohesin for steady-state transcriptional circuits, long-term studies are hampered by essential functions of co...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314343/ https://www.ncbi.nlm.nih.gov/pubmed/35879286 http://dx.doi.org/10.1038/s41467-022-31892-2 |