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The RalGAPα1–RalA signal module protects cardiac function through regulating calcium homeostasis

Sarcoplasmic/endoplasmic reticulum calcium ATPase SERCA2 mediates calcium re-uptake from the cytosol into sarcoplasmic reticulum, and its dysfunction is a hallmark of heart failure. Multiple factors have been identified to modulate SERCA2 activity, however, its regulation is still not fully understo...

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Detalles Bibliográficos
Autores principales: Zhu, Sangsang, Quan, Chao, Wang, Ruizhen, Liang, Derong, Su, Shu, Rong, Ping, Zhou, Kun, Yang, Xinyu, Chen, Qiaoli, Li, Min, Du, Qian, Zhang, Jingzi, Fang, Lei, Wang, Hong-Yu, Chen, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314365/
https://www.ncbi.nlm.nih.gov/pubmed/35879328
http://dx.doi.org/10.1038/s41467-022-31992-z