Cargando…

The RalGAPα1–RalA signal module protects cardiac function through regulating calcium homeostasis

Sarcoplasmic/endoplasmic reticulum calcium ATPase SERCA2 mediates calcium re-uptake from the cytosol into sarcoplasmic reticulum, and its dysfunction is a hallmark of heart failure. Multiple factors have been identified to modulate SERCA2 activity, however, its regulation is still not fully understo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Sangsang, Quan, Chao, Wang, Ruizhen, Liang, Derong, Su, Shu, Rong, Ping, Zhou, Kun, Yang, Xinyu, Chen, Qiaoli, Li, Min, Du, Qian, Zhang, Jingzi, Fang, Lei, Wang, Hong-Yu, Chen, Shuai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314365/ https://www.ncbi.nlm.nih.gov/pubmed/35879328 http://dx.doi.org/10.1038/s41467-022-31992-z

Ejemplares similares

Author Correction: The RalGAPα1–RalA signal module protects cardiac function through regulating calcium homeostasis
por: Zhu, Sangsang, et al.
Publicado: (2022)

Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control
por: Chen, Qiaoli, et al.
Publicado: (2019)

Differential involvement of RalA and RalB in colorectal cancer
por: Martin, Timothy D., et al.
Publicado: (2012)

RalA and RalBP1 regulate mitochondrial fission at mitosis
por: Kashatus, David F., et al.
Publicado: (2011)

RalA and RalB differentially regulate development of epithelial tight junctions
por: Hazelett, C. Clayton, et al.
Publicado: (2011)

RalGAPα2 and NLRP3 Orchestrate Tumor Invasion in Colitis-Associated Cancers
por: Cassani, Barbara
Publicado: (2019)

A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action
por: Chen, Xiao-Wei, et al.
Publicado: (2011)

Low expression of RalGAPs associates with the poorer overall survival of head and neck squamous cell carcinoma
por: Liu, Shan, et al.
Publicado: (2021)

RILP suppresses invasion of breast cancer cells by modulating the activity of RalA through interaction with RalGDS
por: Wang, Z, et al.
Publicado: (2015)

The RAL Enigma: Distinct Roles of RALA and RALB in Cancer
por: Richardson, Dillon S., et al.
Publicado: (2022)

Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD
por: Han, Kihoon, et al.
Publicado: (2009)

Different metastasis promotive potency of small G-proteins RalA and RalB in in vivo hamster tumor model
por: Rybko, Vera A, et al.
Publicado: (2011)

RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation
por: Pollock, Sarah R., et al.
Publicado: (2019)

Breaking up is hard to do: RalA, mitochondrial fission and cancer
por: Kashatus, David F., et al.
Publicado: (2011)

TD-60 links RalA GTPase function to the CPC in mitosis
por: Papini, Diana, et al.
Publicado: (2015)

RalR (a DNase) and RalA (a small RNA) form a type I toxin–antitoxin system in Escherichia coli
por: Guo, Yunxue, et al.
Publicado: (2014)

Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
por: Wang, Shifeng, et al.
Publicado: (2023)

RalA Suppresses Early Stages of Ras-Induced Squamous Cell Carcinoma Progression
por: Sowalsky, Adam G., et al.
Publicado: (2009)

The GTPase RalA Regulates Different Steps of the Secretory Process in Pancreatic β-Cells
por: Ljubicic, Sanda, et al.
Publicado: (2009)

PGE2 Promotes Renal Carcinoma Cell Invasion through Activated RalA
por: Li, Zhenyu, et al.
Publicado: (2012)

NMR resonance assignments for the active and inactive conformations of the small G protein RalA
por: Shafiq, Arooj, et al.
Publicado: (2020)

RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal
por: Hussain, Syed S., et al.
Publicado: (2021)

Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes
por: xia, Wenmin, et al.
Publicado: (2023)

RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer
por: Wang, Pengpeng, et al.
Publicado: (2020)

Sec5 and Exo84 Mediate Distinct Aspects of RalA-Dependent Cell Polarization
por: Hazelett, C. Clayton, et al.
Publicado: (2012)

Identification and Characterisation of the RalA-ERp57 Interaction: Evidence for GDI Activity of ERp57
por: Brymora, Adam, et al.
Publicado: (2012)

The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer
por: Thies, Katie A., et al.
Publicado: (2021)

FOXD1-dependent RalA-ANXA2-Src complex promotes CTC formation in breast cancer
por: Long, Yufei, et al.
Publicado: (2022)

Evaluation and characterization of anti-RalA autoantibody as a potential serum biomarker in human prostate cancer
por: Li, Jitian, et al.
Publicado: (2016)

Possible predictive significance of serum RalA autoantibodies on relapse-free survival in patients with colorectal cancer
por: Ushigome, Mitsunori, et al.
Publicado: (2021)

CTA at RAL
por: Patargias, George
Publicado: (2022)

A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes
por: Karunanithi, Sheelarani, et al.
Publicado: (2014)

Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma
por: Tian, Lu, et al.
Publicado: (2021)

Direct binding of RalA to PKCη and its crucial role in morphological change during keratinocyte differentiation
por: Shirai, Yasuhito, et al.
Publicado: (2011)

Roger Clifft (RAL)
Publicado: (1977)

RAL PPD seminar
Publicado: (2016)

RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth
por: Kano, Takuya, et al.
Publicado: (2021)

Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole–Based RalA Inhibitors Against Hepatocellular Carcinoma
por: Wang, Yuting, et al.
Publicado: (2021)

Ral activation promotes melanomagenesis
por: Zipfel, Patty A., et al.
Publicado: (2010)

ECFA-RAL Topical Meeting
por: European Committee for Future Accelerators. Geneva, et al.
Publicado: (1983)

Cannot write session to /tmp/vufind_sessions/sess_k3sb96s5d99pqbmje1kucq30bd