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PI3Kδ activity controls plasticity and discriminates between EMT and stemness based on distinct TGFβ signaling
The stem cells involved in formation of the complex human body are epithelial cells that undergo apicobasal polarization and form a hollow lumen. Epithelial plasticity manifests as epithelial to mesenchymal transition (EMT), a process by which epithelial cells switch their polarity and epithelial fe...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314410/ https://www.ncbi.nlm.nih.gov/pubmed/35879421 http://dx.doi.org/10.1038/s42003-022-03637-w |