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Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153

Bone mass is maintained by the balance between osteoclast-induced bone resorption and osteoblast-triggered bone formation. In inflammatory arthritis such as rheumatoid arthritis (RA), however, increased osteoclast differentiation and activity skew this balance resulting in progressive bone loss. O-G...

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Detalles Bibliográficos
Autores principales: Li, Yi-Nan, Chen, Chih-Wei, Trinh-Minh, Thuong, Zhu, Honglin, Matei, Alexandru-Emil, Györfi, Andrea-Hermina, Kuwert, Frederic, Hubel, Philipp, Ding, Xiao, Manh, Cuong Tran, Xu, Xiaohan, Liebel, Christoph, Fedorchenko, Vladyslav, Liang, Ruifang, Huang, Kaiyue, Pfannstiel, Jens, Huang, Min-Chuan, Lin, Neng-Yu, Ramming, Andreas, Schett, Georg, Distler, Jörg H. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314416/
https://www.ncbi.nlm.nih.gov/pubmed/35879285
http://dx.doi.org/10.1038/s41413-022-00218-9