Empagliflozin mitigates endothelial inflammation and attenuates endoplasmic reticulum stress signaling caused by sustained glycocalyx disruption

The disruption of the endothelial cell (EC) glycocalyx (GCX) leads to cellular dysfunction promoting inflammation and cardiovascular disease progression. Recent studies have shown that empagliflozin (EMPA; Jardiance), a sodium-glucose cotransporter 2 inhibitor used in the treatment of type 2 diabete...

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Detalles Bibliográficos
Autores principales: Campeau, Marc-Antoine, Leask, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314417/
https://www.ncbi.nlm.nih.gov/pubmed/35879337
http://dx.doi.org/10.1038/s41598-022-16763-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314417/
https://www.ncbi.nlm.nih.gov/pubmed/35879337
http://dx.doi.org/10.1038/s41598-022-16763-6

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