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Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis

Therapeutic targeting of angiogenesis in glioblastoma has yielded mixed outcomes. Investigation of tumor-associated angiogenesis has focused on the factors that stimulate the sprouting, migration, and hyperproliferation of the endothelial cells. However, little is known regarding the processes under...

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Detalles Bibliográficos
Autores principales: Bae, Eunnyung, Huang, Ping, Müller-Greven, Gaёlle, Hambardzumyan, Dolores, Sloan, Andrew Edward, Nowacki, Amy S., Marko, Nicholas, Carlin, Cathleen R., Gladson, Candece L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314429/
https://www.ncbi.nlm.nih.gov/pubmed/35879332
http://dx.doi.org/10.1038/s41467-022-31981-2