Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo

Parents transmit genetic and epigenetic information to their offspring. Maternal effect genes regulate the offspring epigenome to ensure normal development. Here we report that the epigenetic regulator SMCHD1 has a maternal effect on Hox gene expression and skeletal patterning. Maternal SMCHD1, pres...

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Detalles Bibliográficos
Autores principales: Benetti, Natalia, Gouil, Quentin, Tapia del Fierro, Andres, Beck, Tamara, Breslin, Kelsey, Keniry, Andrew, McGlinn, Edwina, Blewitt, Marnie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314430/
https://www.ncbi.nlm.nih.gov/pubmed/35879318
http://dx.doi.org/10.1038/s41467-022-32057-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314430/
https://www.ncbi.nlm.nih.gov/pubmed/35879318
http://dx.doi.org/10.1038/s41467-022-32057-x

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