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Distinct Roles of Glutamine Metabolism in Benign and Malignant Cartilage Tumors With IDH Mutations

Enchondromas and chondrosarcomas are common cartilage neoplasms that are either benign or malignant, respectively. The majority of these tumors harbor mutations in either IDH1 or IDH2. Glutamine metabolism has been implicated as a critical regulator of tumors with IDH mutations. Using genetic and ph...

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Detalles Bibliográficos
Autores principales: Zhang, Hongyuan, Puviindran, Vijitha, Nadesan, Puviindran, Ding, Xiruo, Shen, Leyao, Tang, Yuning J, Tsushima, Hidetoshi, Yahara, Yasuhito, Ban, Ga I, Zhang, Guo‐Fang, Karner, Courtney M, Alman, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314601/
https://www.ncbi.nlm.nih.gov/pubmed/35220602
http://dx.doi.org/10.1002/jbmr.4532