The Polymorphic Nuclear Factor NFIB Regulates Hepatic CYP2D6 Expression and Influences Risperidone Metabolism in Psychiatric Patients

The genetic background for interindividual variability of the polymorphic CYP2D6 enzyme activity remains incompletely understood and the role of NFIB genetic polymorphism for this variability was evaluated in this translational study. We investigated the effect of NFIB expression in vitro using 3D l...

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Detalles Bibliográficos
Autores principales: Lenk, Hasan Çağın, Klöditz, Katharina, Johansson, Inger, Smith, Robert Løvsletten, Jukić, Marin M., Molden, Espen, Ingelman‐Sundberg, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314634/
https://www.ncbi.nlm.nih.gov/pubmed/35253216
http://dx.doi.org/10.1002/cpt.2571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314634/
https://www.ncbi.nlm.nih.gov/pubmed/35253216
http://dx.doi.org/10.1002/cpt.2571

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