Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality

The human brain is a complex, three‐dimensional structure. To better recapitulate brain complexity, recent efforts have focused on the development of human‐specific midbrain organoids. Human iPSC‐derived midbrain organoids consist of differentiated and functional neurons, which contain active synaps...

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Detalles Bibliográficos
Autores principales: Sabate‐Soler, Sonia, Nickels, Sarah Louise, Saraiva, Cláudia, Berger, Emanuel, Dubonyte, Ugne, Barmpa, Kyriaki, Lan, Yan Jun, Kouno, Tsukasa, Jarazo, Javier, Robertson, Graham, Sharif, Jafar, Koseki, Haruhiko, Thome, Christian, Shin, Jay W., Cowley, Sally A., Schwamborn, Jens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314680/
https://www.ncbi.nlm.nih.gov/pubmed/35262217
http://dx.doi.org/10.1002/glia.24167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314680/
https://www.ncbi.nlm.nih.gov/pubmed/35262217
http://dx.doi.org/10.1002/glia.24167

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