Cargando…

Reduced HGF/MET Signaling May Contribute to the Synaptic Pathology in an Alzheimer's Disease Mouse Model

Alzheimer's disease (AD) is a neurodegenerative disorder strongly associates with aging. While amyloid plagues and neurofibrillary tangles are pathological hallmarks of AD, recent evidence suggests synaptic dysfunction and physical loss may be the key mechanisms that determine the clinical synd...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Jing, Ma, Xiaokuang, Nehme, Antoine, Cui, Yuehua, Zhang, Le, Qiu, Shenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314739/
https://www.ncbi.nlm.nih.gov/pubmed/35903536
http://dx.doi.org/10.3389/fnagi.2022.954266