Synthesis of Functionalized δ‐Hydroxy‐β‐keto Esters and Evaluation of Their Anti‐inflammatory Properties

δ‐Hydroxy‐β‐keto esters and δ,β‐dihydroxy esters are characteristic structural motifs of statin‐type natural products and drug candidates. Here, we describe the synthesis of functionalized δ‐hydroxy‐β‐keto esters in good yields and excellent enantioselectivities using Chan's diene and modified...

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Detalles Bibliográficos
Autores principales: Grosse, Michel, Günther, Kerstin, Jordan, Paul M., Roman, Dávid, Werz, Oliver, Beemelmanns, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314795/
https://www.ncbi.nlm.nih.gov/pubmed/35244320
http://dx.doi.org/10.1002/cbic.202200073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314795/
https://www.ncbi.nlm.nih.gov/pubmed/35244320
http://dx.doi.org/10.1002/cbic.202200073

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