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Activity and toxicity of intramuscular 1000 iu/m(2) polyethylene glycol‐E. coli L‐asparaginase in the UKALL 2003 and UKALL 2011 clinical trials
In successive UK clinical trials (UKALL 2003, UKALL 2011) for paediatric acute lymphoblastic leukaemia (ALL), polyethylene glycol‐conjugated E. coli L‐asparaginase (PEG‐EcASNase) 1000 iu/m(2) was administered intramuscularly with risk‐stratified treatment. In induction, patients received two PEG‐EcA...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314843/ https://www.ncbi.nlm.nih.gov/pubmed/35348200 http://dx.doi.org/10.1111/bjh.18158 |