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Activity and toxicity of intramuscular 1000 iu/m(2) polyethylene glycol‐E. coli L‐asparaginase in the UKALL 2003 and UKALL 2011 clinical trials

In successive UK clinical trials (UKALL 2003, UKALL 2011) for paediatric acute lymphoblastic leukaemia (ALL), polyethylene glycol‐conjugated E. coli L‐asparaginase (PEG‐EcASNase) 1000 iu/m(2) was administered intramuscularly with risk‐stratified treatment. In induction, patients received two PEG‐EcA...

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Detalles Bibliográficos
Autores principales:	Sidhu, Jasmeet, Masurekar, Ashish Narayan, Gogoi, Manash Pratim, Fong, Caroline, Ioannou, Tasos, Lodhi, Taha, Parker, Catriona, Liu, Jizhong, Kirkwood, Amy A., Moorman, Anthony V., Das, Kiranmoy, Goulden, Nicholas J., Vora, Ajay, Saha, Vaskar, Krishnan, Shekhar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Paediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314843/ https://www.ncbi.nlm.nih.gov/pubmed/35348200 http://dx.doi.org/10.1111/bjh.18158

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