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The Protein‐Templated Synthesis of Enzyme‐Generated Aptamers

Inspired by the chemical synthesis of molecularly imprinted polymers, we demonstrated for the first time, the protein‐target mediated synthesis of enzyme‐generated aptamers (EGAs). We prepared pre‐polymerisation mixtures containing different ratios of nucleotides, an initiator sequence and protein t...

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Detalles Bibliográficos
Autores principales: Vacacela, Julio, Schaap‐Johansen, Anna‐Lisa, Manikova, Patricia, Marcatili, Paolo, Prado, Marta, Sun, Yi, Ashley, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314878/
https://www.ncbi.nlm.nih.gov/pubmed/35167174
http://dx.doi.org/10.1002/anie.202201061